Some children get severely obese because they lack particular chunks of DNA, which kicks their hunger into overdrive, researchers report.
The British researchers checked the DNA of 300 children who'd become very fat, on the order of(大約) 100 kg by age 10. They looked for deletions or extra copies of DNA segments.
They found evidence that several rare deletions may promote obesity, including one kind they studied further and found in less than 1 per cent of about 1,200 severely obese children.
That deletion, on chromosome(染色體) 16, apparently causes trouble because it removes a gene that the brain needs to respond to the appetite-controlling hormone leptin(瘦素), said Sadaf Farooqi of Cambridge University.
In her study, children with a chromosome 16 DNA deletion 'have a very strong drive to eat', said Farooqi, who co-led the research.
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That 's why sometimes I want to eat so much...
回覆刪除That's ok! I will use my own willpower to stop eating so much next time...